full transcript

From the Ted Talk by Helen M. Farrell: What is depression?

Unscramble the Blue Letters

Depression is the leading cause of disability in the world. In the uientd States, close to 10% of adults sgrlugte with depression. But because it's a mental ineslls, it can be a lot harder to understand than, say, high cholesterol. One mjaor source of confusion is the difference between having depression and just feeling deeprssed. Almost everyone feles down from time to time. Getting a bad grade, losnig a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical depression is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive wekes, and significantly ieetrefrns with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally enjoy, changes in appetite, feeling worthless or excessively guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a diagnosis of depression. And it's not just biheaavorl symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include sllemar foantrl lobes and hippocampal volumes. On a more microscale, depression is associated with a few things: the abnormal tisnsmoirasn or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and dnoipame, blunted circadian rhythms, or sifcipec changes in the REM and slow-wave parts of your seelp cycle, and hormone aamibrltoeins, such as high cortisol and detilaoerugn of thyroid hromneos. But neuroscientists still don't have a complete picture of what causes depression. It seems to have to do with a complex interaction between geens and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because dosrsepien symptoms are intangible, it's hard to know who might look fine but is actually struggling. According to the National Institute of Mental Health, it takes the areavge preosn suffering with a mental illness over ten years to ask for help. But there are very effective treatments. Medications and therapy cmelenmopt each other to boost brain chemicals. In extreme cases, electroconvulsive therapy, which is like a controlled seizure in the patient's brain, is also very hlupefl. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, egncourae them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or making a list of questions to ask a doctor. To someone with depression, these first steps can seem iomutsanunrlbe. If they feel guilty or ashamed, piont out that depression is a medical condition, just like asthma or diabetes. It's not a wnsakees or a personality tairt, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid cnaimropg it to times you've felt down. Comparing what they're experiencing to normal, temporary feelings of sadness can make them feel guilty for struggling. Even just talking about depression openly can help. For example, research shows that asking someone about suicidal tgthhous actually reduces their suicide risk. Open conversations about maentl illness help erdoe stigma and make it easier for people to ask for help. And the more patients seek tenmertat, the more sstiicntes will leran about depression, and the better the treatments will get.

Open Cloze

Depression is the leading cause of disability in the world. In the ______ States, close to 10% of adults ________ with depression. But because it's a mental _______, it can be a lot harder to understand than, say, high cholesterol. One _____ source of confusion is the difference between having depression and just feeling _________. Almost everyone _____ down from time to time. Getting a bad grade, ______ a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical depression is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive _____, and significantly __________ with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally enjoy, changes in appetite, feeling worthless or excessively guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a diagnosis of depression. And it's not just __________ symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include _______ _______ lobes and hippocampal volumes. On a more microscale, depression is associated with a few things: the abnormal ____________ or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and ________, blunted circadian rhythms, or ________ changes in the REM and slow-wave parts of your _____ cycle, and hormone _____________, such as high cortisol and ____________ of thyroid ________. But neuroscientists still don't have a complete picture of what causes depression. It seems to have to do with a complex interaction between _____ and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because __________ symptoms are intangible, it's hard to know who might look fine but is actually struggling. According to the National Institute of Mental Health, it takes the _______ ______ suffering with a mental illness over ten years to ask for help. But there are very effective treatments. Medications and therapy __________ each other to boost brain chemicals. In extreme cases, electroconvulsive therapy, which is like a controlled seizure in the patient's brain, is also very _______. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, _________ them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or making a list of questions to ask a doctor. To someone with depression, these first steps can seem ______________. If they feel guilty or ashamed, _____ out that depression is a medical condition, just like asthma or diabetes. It's not a ________ or a personality _____, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid _________ it to times you've felt down. Comparing what they're experiencing to normal, temporary feelings of sadness can make them feel guilty for struggling. Even just talking about depression openly can help. For example, research shows that asking someone about suicidal ________ actually reduces their suicide risk. Open conversations about ______ illness help _____ stigma and make it easier for people to ask for help. And the more patients seek _________, the more __________ will _____ about depression, and the better the treatments will get.

Solution

  1. feels
  2. illness
  3. sleep
  4. depression
  5. thoughts
  6. weakness
  7. genes
  8. major
  9. specific
  10. depressed
  11. smaller
  12. transmission
  13. encourage
  14. struggle
  15. scientists
  16. erode
  17. average
  18. trait
  19. learn
  20. insurmountable
  21. point
  22. frontal
  23. interferes
  24. dopamine
  25. treatment
  26. hormones
  27. losing
  28. deregulation
  29. helpful
  30. weeks
  31. united
  32. abnormalities
  33. person
  34. comparing
  35. behavioral
  36. mental
  37. complement

Original Text

Depression is the leading cause of disability in the world. In the United States, close to 10% of adults struggle with depression. But because it's a mental illness, it can be a lot harder to understand than, say, high cholesterol. One major source of confusion is the difference between having depression and just feeling depressed. Almost everyone feels down from time to time. Getting a bad grade, losing a job, having an argument, even a rainy day can bring on feelings of sadness. Sometimes there's no trigger at all. It just pops up out of the blue. Then circumstances change, and those sad feelings disappear. Clinical depression is different. It's a medical disorder, and it won't go away just because you want it to. It lingers for at least two consecutive weeks, and significantly interferes with one's ability to work, play, or love. Depression can have a lot of different symptoms: a low mood, loss of interest in things you'd normally enjoy, changes in appetite, feeling worthless or excessively guilty, sleeping either too much or too little, poor concentration, restlessness or slowness, loss of energy, or recurrent thoughts of suicide. If you have at least five of those symptoms, according to psychiatric guidelines, you qualify for a diagnosis of depression. And it's not just behavioral symptoms. Depression has physical manifestations inside the brain. First of all, there are changes that could be seen with the naked eye and X-ray vision. These include smaller frontal lobes and hippocampal volumes. On a more microscale, depression is associated with a few things: the abnormal transmission or depletion of certain neurotransmitters, especially serotonin, norepinephrine, and dopamine, blunted circadian rhythms, or specific changes in the REM and slow-wave parts of your sleep cycle, and hormone abnormalities, such as high cortisol and deregulation of thyroid hormones. But neuroscientists still don't have a complete picture of what causes depression. It seems to have to do with a complex interaction between genes and environment, but we don't have a diagnostic tool that can accurately predict where or when it will show up. And because depression symptoms are intangible, it's hard to know who might look fine but is actually struggling. According to the National Institute of Mental Health, it takes the average person suffering with a mental illness over ten years to ask for help. But there are very effective treatments. Medications and therapy complement each other to boost brain chemicals. In extreme cases, electroconvulsive therapy, which is like a controlled seizure in the patient's brain, is also very helpful. Other promising treatments, like transcranial magnetic stimulation, are being investigated, too. So, if you know someone struggling with depression, encourage them, gently, to seek out some of these options. You might even offer to help with specific tasks, like looking up therapists in the area, or making a list of questions to ask a doctor. To someone with depression, these first steps can seem insurmountable. If they feel guilty or ashamed, point out that depression is a medical condition, just like asthma or diabetes. It's not a weakness or a personality trait, and they shouldn't expect themselves to just get over it anymore than they could will themselves to get over a broken arm. If you haven't experienced depression yourself, avoid comparing it to times you've felt down. Comparing what they're experiencing to normal, temporary feelings of sadness can make them feel guilty for struggling. Even just talking about depression openly can help. For example, research shows that asking someone about suicidal thoughts actually reduces their suicide risk. Open conversations about mental illness help erode stigma and make it easier for people to ask for help. And the more patients seek treatment, the more scientists will learn about depression, and the better the treatments will get.

Frequently Occurring Word Combinations

ngrams of length 2

collocation frequency
mental illness 2
feel guilty 2

Important Words

  1. ability
  2. abnormal
  3. abnormalities
  4. accurately
  5. adults
  6. anymore
  7. appetite
  8. area
  9. argument
  10. arm
  11. ashamed
  12. asthma
  13. average
  14. avoid
  15. bad
  16. behavioral
  17. blue
  18. blunted
  19. boost
  20. brain
  21. bring
  22. broken
  23. cases
  24. change
  25. chemicals
  26. cholesterol
  27. circadian
  28. circumstances
  29. clinical
  30. close
  31. comparing
  32. complement
  33. complete
  34. complex
  35. concentration
  36. condition
  37. confusion
  38. consecutive
  39. controlled
  40. conversations
  41. cortisol
  42. cycle
  43. day
  44. depletion
  45. depressed
  46. depression
  47. deregulation
  48. diabetes
  49. diagnosis
  50. diagnostic
  51. difference
  52. disability
  53. disappear
  54. disorder
  55. doctor
  56. dopamine
  57. easier
  58. effective
  59. electroconvulsive
  60. encourage
  61. energy
  62. enjoy
  63. environment
  64. erode
  65. excessively
  66. expect
  67. experienced
  68. experiencing
  69. extreme
  70. eye
  71. feel
  72. feeling
  73. feelings
  74. feels
  75. felt
  76. fine
  77. frontal
  78. genes
  79. gently
  80. grade
  81. guidelines
  82. guilty
  83. hard
  84. harder
  85. health
  86. helpful
  87. high
  88. hippocampal
  89. hormone
  90. hormones
  91. illness
  92. include
  93. institute
  94. insurmountable
  95. intangible
  96. interaction
  97. interest
  98. interferes
  99. investigated
  100. job
  101. leading
  102. learn
  103. lingers
  104. list
  105. lobes
  106. losing
  107. loss
  108. lot
  109. love
  110. magnetic
  111. major
  112. making
  113. manifestations
  114. medical
  115. medications
  116. mental
  117. microscale
  118. mood
  119. naked
  120. national
  121. neuroscientists
  122. neurotransmitters
  123. norepinephrine
  124. normal
  125. offer
  126. open
  127. openly
  128. options
  129. parts
  130. patients
  131. people
  132. person
  133. personality
  134. physical
  135. picture
  136. play
  137. point
  138. poor
  139. pops
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  141. promising
  142. psychiatric
  143. qualify
  144. questions
  145. rainy
  146. recurrent
  147. reduces
  148. rem
  149. research
  150. restlessness
  151. rhythms
  152. risk
  153. sad
  154. sadness
  155. scientists
  156. seek
  157. seizure
  158. serotonin
  159. show
  160. shows
  161. significantly
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  164. slowness
  165. smaller
  166. source
  167. specific
  168. states
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  170. stigma
  171. stimulation
  172. struggle
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  174. suffering
  175. suicidal
  176. suicide
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  180. tasks
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  184. therapy
  185. thoughts
  186. thyroid
  187. time
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  189. tool
  190. trait
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  192. transmission
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  195. trigger
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  198. vision
  199. volumes
  200. weakness
  201. weeks
  202. work
  203. world
  204. worthless
  205. years